![]() ![]() A prospective randomized clinical trial showed an incidence of almost 19% SSIs following high risk lower extremity fracture surgery. Wound healing is particularly challenging following high-energy trauma, and frequently contribute to postoperative wound dehiscence and surgical site infections (SSIs). Wound complications within the realm of orthopedic trauma surgery are a major concern. Rational use of NWPT should be based on the presence of patient’s condition and risk factors. NPWT appeared to be an efficient alternative to help prevent SSIs and wound dehiscence on closed incisions in orthopedic trauma surgery. However, no statistically significant difference was found in the length of hospital stay. NPWT resulted in a significantly lower incidence of deep SSI, superficial SSI, and wound dehiscence than conventional wound dressings. ResultsĪ total of 6 studies including 2 randomized controlled trials (RCTs) and 4 cohort studies met our inclusion criteria. Meta-analysis was performed using RevMan 5.3 software. Cochrane collaboration’s tool and the Newcastle–Ottawa Scale (NOS) were used to evaluate literature qualities. The outcome measures included deep surgical site infection (SSI), superficial SSI wound dehiscence and length of hospital stay. MethodsĪ systematic search was performed in PubMed, Embase, and the Cochrane Library databases. This meta-analysis was performed to determine the efficacy of negative pressure wound therapy (NPWT) versus conventional wound dressings for closed incisions in orthopedic trauma surgery. ![]()
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